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genego metacore tool  (GeneGo Inc)

 
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    GeneGo Inc genego metacore tool
    ESR1 transcription targets regulated in CF. Network adapted from Genego <t>Metacore.</t> Grey lozenges indicate genes up-regulated in CF (including ESR1); white lozenges indicate genes down-regulated in CF. Arrows represent effect predicted by Metacore of ESR1 on gene, as shown on key. Gene names shown in bold are those whose direction of regulation in CF would be reinforced by ESR1, based on its predicted effect.
    Genego Metacore Tool, supplied by GeneGo Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/genego+metacore+tool/pmc03637641-288-13-12?v=GeneGo+Inc
    Average 90 stars, based on 1 article reviews
    genego metacore tool - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies"

    Article Title: Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies

    Journal: Respiratory Research

    doi: 10.1186/1465-9921-14-38

    ESR1 transcription targets regulated in CF. Network adapted from Genego Metacore. Grey lozenges indicate genes up-regulated in CF (including ESR1); white lozenges indicate genes down-regulated in CF. Arrows represent effect predicted by Metacore of ESR1 on gene, as shown on key. Gene names shown in bold are those whose direction of regulation in CF would be reinforced by ESR1, based on its predicted effect.
    Figure Legend Snippet: ESR1 transcription targets regulated in CF. Network adapted from Genego Metacore. Grey lozenges indicate genes up-regulated in CF (including ESR1); white lozenges indicate genes down-regulated in CF. Arrows represent effect predicted by Metacore of ESR1 on gene, as shown on key. Gene names shown in bold are those whose direction of regulation in CF would be reinforced by ESR1, based on its predicted effect.

    Techniques Used:



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    Image Search Results


    ESR1 transcription targets regulated in CF. Network adapted from Genego Metacore. Grey lozenges indicate genes up-regulated in CF (including ESR1); white lozenges indicate genes down-regulated in CF. Arrows represent effect predicted by Metacore of ESR1 on gene, as shown on key. Gene names shown in bold are those whose direction of regulation in CF would be reinforced by ESR1, based on its predicted effect.

    Journal: Respiratory Research

    Article Title: Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies

    doi: 10.1186/1465-9921-14-38

    Figure Lengend Snippet: ESR1 transcription targets regulated in CF. Network adapted from Genego Metacore. Grey lozenges indicate genes up-regulated in CF (including ESR1); white lozenges indicate genes down-regulated in CF. Arrows represent effect predicted by Metacore of ESR1 on gene, as shown on key. Gene names shown in bold are those whose direction of regulation in CF would be reinforced by ESR1, based on its predicted effect.

    Article Snippet: The full list of 388 regulated probesets was also submitted to the GeneGo Metacore tool ( http://thomsonreuters.com/products_services/science/systems-biology/ ), which comprises an integrated knowledge database and software suite for pathway analysis of gene lists.

    Techniques:

    Shared significantly altered gene sets between PD, HGPS, AD and PM, determined using GeneGO MetaCore TM enrichment analysis (adjusted p -value ≤0.05): a ) shared canonical pathways; b ) shared GO biological processes. *: significant overlap by Fisher’s exact test ( p -value ≤0.05)

    Journal: BMC Medical Genomics

    Article Title: Comparative transcriptome analysis of Parkinson’s disease and Hutchinson-Gilford progeria syndrome reveals shared susceptible cellular network processes

    doi: 10.1186/s12920-020-00761-6

    Figure Lengend Snippet: Shared significantly altered gene sets between PD, HGPS, AD and PM, determined using GeneGO MetaCore TM enrichment analysis (adjusted p -value ≤0.05): a ) shared canonical pathways; b ) shared GO biological processes. *: significant overlap by Fisher’s exact test ( p -value ≤0.05)

    Article Snippet: Alterations in the activity of pathways and biological processes were investigated using the software tool GeneGO MetaCore TM ( https://portal.genego.com/ ).

    Techniques:

    a Overlap of significantly altered subnetworks between PD, HGPS, AD and PM, determined using GeneGO MetaCore TM network analysis. b Shared GO biological processes among the subnetworks for PD, HGPS, AD and PM. *: significant overlap by Fisher’s exact test ( p -value ≤0.05)

    Journal: BMC Medical Genomics

    Article Title: Comparative transcriptome analysis of Parkinson’s disease and Hutchinson-Gilford progeria syndrome reveals shared susceptible cellular network processes

    doi: 10.1186/s12920-020-00761-6

    Figure Lengend Snippet: a Overlap of significantly altered subnetworks between PD, HGPS, AD and PM, determined using GeneGO MetaCore TM network analysis. b Shared GO biological processes among the subnetworks for PD, HGPS, AD and PM. *: significant overlap by Fisher’s exact test ( p -value ≤0.05)

    Article Snippet: Alterations in the activity of pathways and biological processes were investigated using the software tool GeneGO MetaCore TM ( https://portal.genego.com/ ).

    Techniques: